Femoral Neck Fracture: Drug Therapy

Therapy goals

  • Pain relief.
  • Prevention of thrombosis (vascular disease in which a blood clot (thrombus) forms in a blood vessel).
  • Avoidance of complications (eg, infections).

Therapy recommendations

  • Analgesia (pain relief) according to WHO staging scheme.
    • Non-opioid analgesic(acetaminophen, first-line agent).
    • Low-potency opioid analgesic (e.g., tramadol) + non-opioid analgesic.
    • High-potency opioid analgesic (eg, morphine) + non-opioid analgesic.
  • Thromboprophylaxis (see below Thrombosis) [hip fractures are among the high-risk factors for thrombosis].
  • Infection prophylaxis (antibiotic prophylaxis) reduces the rate of superficial and deepwound infections, as well as urinary and respiratory infections in patients withfemoral neck fractures; a single dose of antibiotics with the onset of anesthesia induction is sufficient for theroutine
  • See also under “Further therapy.”