The following are the most important diseases or complications that may be contributed to by genital herpes infection:
Respiratory system (J00-J99)
- Pneumonia (pneumonia)
Eyes and eye appendages (H00-H59) (primarily HSV-1).
- Blepharitis (eyelid inflammation).
- Corneal perforation
- Corneal ulcer (ulcer)
- Keratitis (inflammation of the cornea)
- Conjunctivitis (conjunctivitis)
- Uveitis (medium inflammation of the skin of the eye)
- Visual acuity reduction (visual acuity reduction)
Certain conditions originating in the perinatal period (P00-P96).
- Herpes neonatorum (almost always HSV-2; neonatal herpes) – transmission of infection to the child during birth (infection via the birth canal) resulting in severe infection of the newborn, which may lead to death of the child; neonatal risk of infection is 40-50% with maternal (mother’s) primary infection in the last 4 weeks before birth
Skin and subcutaneous (L00-L99).
- Eczema herpeticatum – superinfected dermatosis (skin disease); usually occurs with coexisting atopic eczema (neurodermatitis).
- Erythema exsudativum multiforme (synonyms: erythema multiforme, cocard erythema, disc rose) – in the upper corium (dermis) occurring acute inflammation, which leads to typical cocard-shaped lesions; a distinction is made between a minor and a major form.
Infectious and parasitic diseases (A00-B99).
- Herpes panaritium – inflammation of the finger or toe caused by the herpes virus.
- HSV sepsis (blood poisoning) with encephalitis (brain inflammation) and multi-organ infection.
- Septic shock – complex circulatory failure due to blood poisoning.
Liver, gallbladder, and bile ducts – pancreas (pancreas) (K70-K77; K80-K87).
- Hepatitis (inflammation of the liver)
Mouth, esophagus (esophagus), stomach, and intestines (K00-K67; K90-K93).
- Gingivostomatitis (inflammation of the mouth and gums) (primarily HSV-1).
- Esophagitis (esophagitis).
Psyche – nervous system (F00-F99; G00-G99)
- Emotional conflicts
- Herpes encephalitis (HSV encephalitis; brain inflammation) – most common necrotizing encephalitis (approximately 50%).
- 30% after primary infection
- – 70% as recurrent herpes
- High lethality (mortality rate; up to 70%); many surviving patients retain residuals
- Meningitis (meningitis).
Genitourinary system (kidneys, urinary tract – reproductive organs) (N00-N99).
- Balanitis (acorn inflammation).
- Renal insufficiency (kidney weakness)
- Prostatitis (prostatitis)
- Urethritis (inflammation of the urethra)
- Vulvovaginitis herpetica – inflammation caused by herpes viruses, which affects the vulva (set of external primary sexual organs) and vagina (vagina) together.