Polymorphous Light Dermatosis: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin [patchy erythema (areal redness of skin), followed by: bullae (blisters), papules (vesicles), papulo-vesicles (mixture of papule and vesicle (vesicle)), plaques] Predilection sites (typical sites for the appearance of … Polymorphous Light Dermatosis: Examination

Polymorphous Light Dermatosis: Drug Therapy

Therapeutic target Alleviation of symptoms Therapy recommendations Beta-carotene Nicotinamide and folic acid Corticosteroids; azathioprine in extreme individual cases. Antihistamines can relieve the itching See also under “Further therapy“. All agents have in common a relatively limited efficacy. In experimental studies, efficacy has been demonstrated for E. coli extract. Supplements (dietary supplements; vital substances) Appropriate dietary … Polymorphous Light Dermatosis: Drug Therapy

Polymorphous Light Dermatosis: Prevention

Limiting sun exposure contributes to the prevention of polymorphous light dermatosis. Prophylaxis is of significant importance. By becoming accustomed to light by means of, for example, phototherapy to general light protection measures (sunscreens with a high sun protection factor (UV-A and UV-B protection), the wearing of caps/hats, etc.), the affected person can prevent or reduce … Polymorphous Light Dermatosis: Prevention

Polymorphous Light Dermatosis: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate polymorphous light dermatosis: Initially, itching occurs, followed by patchy redness of the skin. Thereafter, the following efflorescences (skin changes; skin bloom) may occur: Bullae (blisters) Papules (vesicles) Papulo-vesicle – a mixture of papule and vesicle (vesicle) represents. Plaques (areal or plate-like substance proliferation of the skin). Predilection sites … Polymorphous Light Dermatosis: Symptoms, Complaints, Signs

Polymorphous Light Dermatosis: Causes

Pathogenesis (disease development) The exact cause of polymorphous light dermatosis is not known. In recent studies, it is thought that immune regulation is disrupted after UV exposure. About 75% of affected individuals have exclusive UV-A sensitivity. 15% show UV-A/B sensitivity. It has been observed that polymorphous light dermatosis also occurs from sun exposure behind window … Polymorphous Light Dermatosis: Causes

Polymorphous Light Dermatosis: Therapy

General measures Prophylactic measures (staged scheme according to progression): Light acclimation in spring/summer (about 75% of affected individuals have exclusive UV-A sensitivity, 15% show UV-A/B sensitivity). Sunscreen with broad-spectrum effect and sun protection factor 30-50 with the addition of antioxidants. In acute polymorphous light dermatosis: Sunscreen External (external) anti-inflammatory (anti-inflammatory) measures, corticosteroid creams if necessary. … Polymorphous Light Dermatosis: Therapy

Polymorphous Light Dermatosis: Medical History

Medical history (history of illness) represents an important component in the diagnosis of polymorphous light dermatosis. Family history Are there frequent skin diseases in your family? Social anamnesis Current medical history/systemic history (somatic and psychological complaints). What changes have you noticed in the skin (blisters, vesicles, etc.)? How long have these changes existed? Have they … Polymorphous Light Dermatosis: Medical History

Polymorphous Light Dermatosis: Or something else? Differential Diagnosis

Skin and subcutaneous (L00-L99). Chronic actinic dermatitis (light sickness). Erythema exsudativum multiforme (synonyms: erythema multiforme, cocard erythema, disc rose) – acute inflammation occurring in the upper corium (dermis), which leads to typical cocard-shaped lesions; a distinction is made between a minor and a major form. Hereditary polymorphous light dermatosis of American Indians. Light urticaria – … Polymorphous Light Dermatosis: Or something else? Differential Diagnosis