Definition – What is pseudocholinesterase? Pseudocholinesterase is an enzyme that cleaves an ester bond with the help of water, this process is also called hydrolytic ester cleavage. The enzyme can be found almost everywhere, especially high concentrations can be found in the blood, liver and pancreas. The enzyme is mainly relevant in the case of … The Pseudocholinesterase
What is dangerous about that? Dangerous is the lack of pseudocholinesterase mainly in operations that require relaxation of the muscles. However, it is only dangerous if it is not recognized that breathing does not resume. Normally, the situation of reawakening is very closely monitored by the anesthesiologists, the anaesthetists. In the event that breathing fails … What is dangerous about that? | The Pseudocholinesterase
Cholinesterase inhibitors are components of various drugs that can be used for a wide range of diseases due to their many different modes of action. Cholinesterases increase the activity of certain cell compounds, which are located in the brain as well as in various organs such as the eyes or the bladder. The available cholinesterase … What are cholinesterase inhibitors?
The active ingredient and the effect of cholinesterase inhibitors Cholinesterase inhibitors are a group of active ingredients that differ slightly in their chemical structure but are characterized by the same basic action. The site of action is the connections between nerve cells (synapses) and the connection between nerve and muscle cells (motor end plate). There, … The active ingredient and the effect of cholinesterase inhibitors | What are cholinesterase inhibitors?
Contraindications – When should a cholinesterase inhibitor not be given? Cholinesterase inhibitors must not be given for different diseases on different organs, as otherwise the disease may worsen and sometimes life-threatening consequences may result. First of all, there are diseases of the heart where there is a disturbance of the electrical impulse conduction (AV-BLock) or … Contraindications – When should a cholinesterase inhibitor not be given? | What are cholinesterase inhibitors?
Poisoning with a cholinesterase inhibitor Poisoning with a cholinesterase inhibitor can occur as a result of excessive use of the drug. Depending on the amount of overdose, different signs of poisoning may appear. Moderate overdose may result in increased tear and saliva flow, muscle twitching, decreased respiratory drive and hypothermia. In case of a severe … Poisoning with a cholinesterase inhibitor | What are cholinesterase inhibitors?
Definition – What is cholinesterase deficiency? Cholinesterase is an enzyme (a substance that speeds up chemical reactions in the body, usually a protein) and is produced in the liver. It plays an important role in the transmission of impulses from nerves to, for example, muscles (see: Motor End Plate). If the liver is damaged by … Cholinesterase deficiency
Effects of cholinesterase deficiency under local anesthesia With local anaesthesia, a cholinesterase deficiency has the consequence that certain local anaesthetics are broken down more slowly. This results in a prolonged anaesthesia of the region, but the fact that the drug has a longer duration of action in the body can also lead to further side … Effects of cholinesterase deficiency under local anesthesia | Cholinesterase deficiency
Definition Bilirubin is produced in the human body during the breakdown of hemoglobin. Haemoglobin is the red blood pigment whose main function is to store oxygen in the blood cells. Human blood owes its red colour to it. Bilirubin, on the other hand, is yellowish to brownish in colour and lipophilic, i.e. it is well … Bilirubin
Bilirubin in urine Bilirubin is normally excreted in humans through the bile and further through the intestines. However, a smaller proportion is also eliminated from the body through the kidneys and thus through urine. The kidneys can only excrete the conjugated or direct bilirubin. Indirect bilirubin is bound in the blood to the protein albumin, … Bilirubin in urine | Bilirubin
Bilirubin in the baby In the womb, the unborn child needs a special form of haemoglobin, called fetal haemoglobin. This binds oxygen more tightly and thus allows the foetus to be supplied with oxygen via the placenta. After birth, this fetal haemoglobin is broken down. A lot of bilirubin is produced at once. At the … Bilirubin in the baby | Bilirubin
What is the GGT value? The term GGT stands for Gamma-GT or also Gamma-Glutamyltranspeptidase or Gamma-Glutamyltransferase. This describes an enzyme that is found in several organs. These include the spleen, small intestine, pancreas, kidney and, above all, the liver, as it has a high turnover of amino acids. The enzyme is membrane-bound and is involved … Liver value GGT
