Products Minocycline is commercially available in the form of film-coated tablets (Minocin). It has been approved in many countries since 1984. Minac capsules are out of commerce. Topical medicines are additionally available in some countries. Structure and properties Minocylcine (C23H27N3O7, Mr = 457.5 g/mol) is present in drugs as minocycline hydrochloride, a yellow, crystalline, hygroscopic … Minocycline
Products Lymecycline is commercially available in the form of capsules (Tetralysal). It was approved in many countries in 2005. Structure and properties Lymecycline (C29H38N4O10, Mr = 602.6 g/mol) is a water-soluble prodrug of the antibiotic tetracycline with the amino acid lysine. Lymecycline is better absorbed than tetracycline. Effects Lymecycline (ATC J01AA04) has bacteriostatic properties against … Lymecycline
Products Tigecycline is commercially available as a dry substance for the preparation of an infusion solution (Tygacil). It has been approved in many countries since 2007. Effects Tigecycline (ATC J01AA12) has bacteriostatic properties. It inhibits translation in bacterial protein synthesis by binding to the 30S subunit of ribosomes and preventing the attachment of aminoacyl-tRNA molecules … Tigecycline
Products Doxycycline is commercially available in the form of tablets, capsules, and as a solution for injection (vibramycin, vibravenous, generic). It has been approved in many countries since 1972. Structure and properties Doxycycline (C22H24N2O8, Mr = 444.4 g/mol) is usually present in drugs as doxycycline hyclate. Some drugs also contain doxycycline monohydrate. These are yellow … Doxycycline: Drug Effects, Side Effects, Dosage and Uses
Background Rosacea is a multiform, chronic inflammatory skin disease of the face that is more common in fair-skinned people. Possible symptoms include transient and persistent skin redness, papules and pustules, nodules, and skin thickening (“bulbous nose“). The exact causes are not fully understood. Treatment options include metronidazole, azelaic acid, doxycycline, isotretinoin, and nonpharmacologic measures. Products … Doxycycline for Rosacea Treatment
Products Sarecycline was approved in the United States in 2018 in tablet form (Seysara). Structure and properties Sarecycline (C24H29N3O8, Mr = 487.5 g/mol) is structurally related to other tetracyclines. Effects Sarecycline has antibacterial effects against and anti-inflammatory properties. Unlike other tetracyclines, it has a narrow spectrum of activity and therefore has a lesser negative effect … Sarecycline
Products Demeclocycline is commercially available as a paste and cement powder (Ledermix). It has been approved in many countries since 1963. Structure and properties Demeclocycline (C21H21ClN2O8, Mr = 464.85 g/mol) Effects Demeclocycline (ATC A01AC01) has antibacterial properties. Indications For pulpitis prophylaxis For conservative treatment of acute pulpitis with vital preservation of the pulp (pulpitis acuta). … Demeclocycline
