Products Efinaconazole is commercially available in the United States in the form of a solution (Jublia). The active ingredient has not yet been registered in many countries. Structure and properties Efinaconazole (C18H22F2N4O, Mr = 348.4 g/mol) structurally belongs to the triazole antifungals. Effects Efinaconazole has antifungal properties. The effects are due to inhibition of lanosterol … Efinaconazole
Products Itraconazole is commercially available in capsule form and as an oral solution (Sporanox, generic). It has been approved in many countries since 1992. Sporanox infusion concentrate is no longer available. Structure and properties Itraconazole (C35H38Cl2N8O4, Mr = 705.6 g/mol) exists as a white powder that is practically insoluble in water. It belongs to the … Itraconazole
Products Luliconazole is commercially available as a cream (Luzu). It was registered in the United States in 2013. The drug is not currently approved in many countries. In Japan, luliconazole has been on the market since 2005. Structure and properties Luliconazole (C14H9Cl2N3S2, Mr = 354.3 g/mol) is a chlorinated imidazole and 1,3-dithiolane derivative. Effects Luliconazole … Luliconazole
Products Miconazole has been approved in many countries since 1981 in the form of an oral gel (Daktarin Oral Gel). Structure and properties Miconazole (C18H14Cl4N2O, Mr = 416.1 g/mol) is an imidazole derivative. It exists in the gel as a base. Effects Miconazole (ATC A01AB09) has antifungal properties against yeasts (Candida), dermatophytes, and other fungi. … Miconazole Mouth Gel