Cortisone Tablets Effects and Side Effects

Products Cortisone tablets are medicinal products which are intended for ingestion and contain active substances from the group of glucocorticoids. The tablets, water-soluble tablets and sustained-release tablets are usually monopreparations, which are often divisible. Glucocorticoids were first used medicinally in the late 1940s. Structure and properties The glucocorticoids contained in the drugs are derived from … Cortisone Tablets Effects and Side Effects

Inhaled Glucocorticoids

Effects Glucocorticoids (ATC R03BA02) have anti-inflammatory, antiallergic, and immunosuppressive properties. The effects are based on binding to intracellular receptors, resulting in an influence on protein expression. In addition, glucocorticoids also exert extragenomic effects. All agents are lipophilic (virtually insoluble in water) and thus enter cells well across the cell membrane. Indications For the treatment of … Inhaled Glucocorticoids

Prednisolone: Drug Effects, Side Effects, Dosage and Uses

Products Prednisolone is commercially available as tablets, eye drops, eye ointment, cream, ointment, solution, foam, and suppositories (Pred Forte, Prednisolone Streuli, Premandol, Spiricort, Ultracortenol). Structure and properties Prednisone (C21H26O5, Mr = 358.434 g/mol) is the prodrug of prednisolone. Effects Prednisolone (ATC H02AB06) has anti-inflammatory, antiallergic, and immunosuppressive properties. Indications Inflammatory non-infectious skin diseases see under … Prednisolone: Drug Effects, Side Effects, Dosage and Uses

Prednisone

Products Prednisone is available in tablet form from several manufacturers (Prednisone Galepharm, Prednisone Axapharm, Prednisone Streuli). Lodotra sustained-release tablets were approved in 2011. Structure and properties Prednisone (C21H26O5, Mr = 358.4 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug of prednisolone. Effects Prednisolone (ATC A07EA03, ATC … Prednisone

Cortisone Acetate

Products Cortisone Ciba (out of trade) Structure and properties Cortisone acetate (C23H30O6, Mr = 402.5 g/mol) Effects, indications See under glucocorticoids

Methylprednisolone

Products Methylprednisolone is commercially available as an ointment, fatty ointment, cream, in tablet form, and as an injection and infusion preparation (e.g., Medrol, generics). Structure and properties Methylprednisolone (C22H30O5, Mr = 374.5 g/mol) Effects Methylprednisolone (ATC D07AA01, ATC D10AA02, ATC H02AB04) is anti-inflammatory, antiallergic, and immunosuppressive.

Triamcinolone Acetonide

Products Triamcinolone acetonide is commercially available as suspension for injection (Kenacort-A), solution for injection (Kenacort-A Solubile, Ledermix), crystal suspension (Triamcort Depot), paste (Kenacort-A Orabase), tincture (Kenacort-A + salicylic acid), nasal spray (Nasacort, Nasacort Allergo), cream (Pevisone + Econazole). Structure and properties Triamcinolone acetonide (C24H31FO6, Mr = 434.5 g/mol) is a white crystalline powder that is … Triamcinolone Acetonide

Triamcinolone Hexacetonide

Products Triamcinolone hexacetonide is commercially available as a suspension for injection (Triamject). It has been approved in many countries since 2014. Structure and properties Triamcinolone hexacetonide (C30H41FO7, Mr = 532.6 g/mol) is a prodrug of triamcinolone acetonide but not of free triamcinolone alcohol. Triamcinolone hexacetonide is hydrolytically activated and is poorly soluble in water because … Triamcinolone Hexacetonide

Budesonide

Products Budesonide has been approved in many countries since 1988. It is included in numerous medicinal products. Structure and properties Budesonide (C25H34O6, Mr = 430.5 g/mol) is a racemate and exists as a white, crystalline, odorless, tasteless powder that is practically insoluble in water. Effects Budesonide is anti-inflammatory, anti-allergic, and immunosuppressive. Indications Obstructive bronchial disease, … Budesonide

Mometasone

Products Mometasone furoate is commercially available as a cream, ointment, emulsion, and solution (Elocom, Monovo, Ovixan). It has been approved in many countries since 1989. This article refers to use on the skin. Nasal sprays are also available; see mometasone nasal spray. In 2020, a fixed combination with indacaterol was approved for asthma therapy (Atectura … Mometasone

Fluticasone

Products The active ingredient fluticasone has been approved in many countries since 1994 and is included in numerous drugs: Powder inhalers (Arnuity Ellipta, Seretide + salmeterol, Relvar Ellipta + vilanterol, Trelegy Ellipta + vilanterol + umeclidinium bromide). Metered dose inhalers (Axotide, Seretide + salmeterol, Flutiform + formoterol). Nasal sprays (Avamys, Nasofan, Dymista + azelastine). Nasal … Fluticasone

Glucocorticoid Eye Drops

Effects Glucocorticoid eye drops have anti-inflammatory, antiallergic, and immunosuppressive properties on the eye. They may increase intraocular pressure and promote infection. Indications Glucocorticoid eye drops are approved for the treatment of noninfectious inflammatory diseases of the anterior segments of the eye. They are also used in combination with antibiotics for infectious diseases of the eye. … Glucocorticoid Eye Drops