Orexin Receptor Antagonists

Products Orexin receptor antagonists are commercially available in tablet form. The first agent in this group to be approved in the United States was suvorexant (Belsomra) in 2014. Lemborexant (Dayvigo) followed in 2019. Structure and properties Orexin receptor antagonists are characterized by a central ring structure to which heterocycles are attached on both sides. Effects … Orexin Receptor Antagonists

Methaqualone

Products Methaqualone was launched in the 1960s and is now off the market in many countries. Toquilone compositum (fixed combination with diphenhydramine) was withdrawn from the market in late 2005. Methaqualone is now one of the more tightly controlled narcotics (schedule a). Structure and properties Methaqualone (C16H14N2O, Mr = 250.3 g/mol) is a quinazoline derivative. … Methaqualone

Chloral Hydrate

Products Chloral hydrate was approved in many countries in 1954 and is commercially available as a solution (Nervifene). Other products such as Medianox and chloraldurate are no longer available. Structure and properties Chloral hydrate (C2H3Cl3O2, Mr = 165.4 g/mol) is in the form of colorless, transparent crystals that are very soluble in water. It has … Chloral Hydrate

Z-Drugs

Products Z-drugs – they are also called Z-substances – are usually taken in the form of film-coated tablets. In addition, other dosage forms such as sustained-release tablets and effervescent tablets are commercially available. Zolpidem (Stilnox) was the first substance from this group to be approved in many countries in 1990. In the literature, alluding to … Z-Drugs

Sleeping Teas

Products Sleep teas are sold in pharmacies and drugstores as open goods and finished medicines. Ingredients Sleep teas contain various sleep-inducing and sedative medicinal drugs. These include: Valerian root Melissa leaves Lavender flowers Passionflower herb Orange blossom Hop cones Effects Sleeping teas have sleep-inducing, sedative and anti-anxiety properties. Fields of application For the treatment of … Sleeping Teas

Stilnox

The drug Stilnox® contains the active ingredient zolpidem. Zolpidem has a similar effect to benzodiazepines. It belongs to the group of so-called GABA agonists, i.e. it stimulates the GABA receptors in the brain, which mediate attenuating processes. Stilnox® thus promotes sleep. Its half-life is about two to three hours. The active ingredient zolpidem is currently … Stilnox

Risk of dependency | Stilnox

Risk of dependency The risk of becoming dependent on Stilnox® is relatively high. This is especially true if the drug is taken for longer than four weeks. To avoid dependence, the therapy should therefore be as short as possible. In addition, the daily dose of a maximum of one film-coated tablet (or half a film-coated … Risk of dependency | Stilnox

Interactions | Stilnox

Interactions If other drugs are taken at the same time as Stilnox® therapy, undesirable interactions may occur. For example, the effect of Stilnox® may be intensified if other sleeping pills, painkillers (e.g. opioids/opioids), antidepressants, antiepileptics or sedatives (tranquilizers) are taken at the same time. The same applies to the antibiotic ciprofloxacin. Alcohol can also intensify … Interactions | Stilnox

Hoggar® Night

The drug Hoggar® Night Tablets is mainly used for the short-term treatment of sleep disorders. It accelerates falling asleep, promotes sleep through the night and has no disturbing influence on the sleep rhythm. Mode of action Hoggar® Night is a drug from the group of sedatives and hypnotics. It is also an antihistamine. Histamine is … Hoggar® Night

Side effects | Hoggar® Night

Side effects The side effects of Hoggar® Night are many and varied, but do not have to be. In addition, the package inserts list each unwanted effect of the drug that has occurred once. In patients with an adrenal gland tumour, the administration of antihistamines, which includes Hoggar® Night, can cause certain substances to be … Side effects | Hoggar® Night

Adumbran

Definition Adumbran is a drug containing the prescription active ingredient Oxazephan, which, due to its sedative effect, is used for the short-term treatment of agitation and sleep disorders. Application areas The calming effect of adumbrans is used, among other things, to alleviate However, in both cases, the use of adumbrans is only suitable for symptomatic … Adumbran