Introduction Alpha-1-antitrypsin belongs to the protein structures, i.e. proteins that float in blood serum. The name comes from the study to identify these proteins. In serum white electrophoresis, these proteins are in the alpha-1 group. Alpha-1-antitrypsin is an antagonist of trypsin, an enzyme that cleaves proteins. This trypsin, which is harmful in the blood, is … Alpha-1-antitrypsin
What happens in Alpha-1-antitrypsin deficiency? Alpha-1-antitrypsin works through two different systems. – One is the adhesion of the defective alpha-1-antitrypsin to the site of origin. The defective protein accumulates in the liver and the liver can no longer adequately perform its other tasks. In newborns, this can lead to severe liver damage, cirrhosis of the … What happens in Alpha-1-antitrypsin deficiency? | Alpha-1-antitrypsin
Consequences of an altered antitrypsin level The increase in alpha-1-antitrypsin itself has hardly any negative consequences for the body and is a normal reaction to abnormal processes in the body. The change in value is therefore an indication of possibly pathological processes in the body, which in turn lead to symptoms of illness. In this … Consequences of an altered antitrypsin level | Alpha-1-antitrypsin
Definition – What is trypsinogen? Trypsinogen is the inactive precursor, a so-called proenzyme, of an enzyme that is produced in the pancreas. Together with the remaining pancreatic secretion, known as pancreatic saliva, the proenzyme trypsinogen is released via the pancreatic ducts into the duodenum, a part of the small intestine. This is where activation to … Trypsinogen
Where is trypsinogen produced? The proenzyme trypsinogen is roughly formulated in the pancreas. This lies transversely in the upper abdomen on the left side of the stomach. The pancreas can also be divided into two parts: The endocrine part produces hormones like insulin for the regulation of the sugar balance, which act within the body. … Where is trypsinogen produced? | Trypsinogen
Alpha-1-Antitrypsin Deficiency The cause of alpha-1-antitrypsin deficiency is often a genetic defect. Alpha-1-antitrypsin is an enzyme that inhibits other enzymes in their function. The enzymes that are inhibited normally have the task of breaking down proteins, which causes them to lose their function. Alpha-1-antitrypsin can therefore also be called a proteinase inhibitor. The enzymes that … Alpha-1-Antitrypsin Deficiency | Trypsinogen
