Pathogenesis (development of disease) Pathogenesis depends on the cause of the disease. Etiology (causes) Biographic causes Genetic burden The likelihood of statin intolerance (statin-associated muscle pain (SAMS)) is increased if patients had two copies of the LILBR5 gene variants Asp247Gly (homozygous): Probability of CK increase was increased almost 1.81-fold (odds ratio [OR]: 1.81; 95% confidence … Muscle Pain (Myalgia): Causes
The following are the most important diseases or complications that may be contributed to by myalgia (muscle pain): Musculoskeletal system and connective tissue (M00-M99). Immune-mediated necrotizing myopathy (NM; form of myositis/muscle inflammation) act, which is considered a rare complication of statin therapy (0.1% of cases). This necessitates immunosuppressive therapy.Clinical presentation: progressive proximal/axial weakness (difficulty standing), … Muscle Pain (Myalgia): Complications
