Heat Stroke and Sunstroke: Or something else? Differential Diagnosis

Differential diagnoses for suspected heat stroke.

Endocrine, nutritional, and metabolic disorders (E00-E90).

  • Pheochromocytoma – neuroendocrine (affecting the nervous system) catecholamine-producing tumor of the chromaffin cells of the adrenal medulla (85% of cases) or sympathetic ganglia (nerve cord that runs along the spine in the thoracic (chest) and abdominal (stomach) regions) (15% of cases).
  • Thyrotoxic crisis – acute and life-threatening metabolic derailment; usually on the ground of existing hyperthyroidism (hyperthyroidism).

Infectious and parasitic diseases (A00-B99).

  • Malaria
  • Tetanus (tetanus)
  • Sepsis (blood poisoning)
  • Typhoid fever

Circulatory system (I00-I99)

  • Apoplexy (stroke)

Psyche – nervous system (F00-F99; G00-G99)

Injuries, poisonings, and other consequences of external causes (S00-T98).

  • Heat exhaustion
  • Heat cramps
  • Heat exhaustion, hydroprive (water deficiency) or saloprive (salt deficiency).
  • Malignant hyperthermia – life-threatening metabolic derailment caused by genetic dysregulation within skeletal muscle; in addition to numerous symptoms, a sharp increase in body temperature occurs.
  • Toxicological diseases
    • Aspirin overdose
    • Anticholinergic toxidrome – symptoms caused by an overdose of anticholinergic drugs.
    • Malignant neuroleptic syndrome (MNS; synonym: malignant neuroleptic syndrome) – side effect of taking neuroleptics (antipsychotics).
    • Serotonin syndrome (synonym: serotonergic syndrome) – complex of symptoms caused by accumulation of the tissue hormone and neurotransmitter serotonin or serotonin-like substances in parts of the body.
    • Drug interactions (amphetamines, heroin, cocaine, MDMA, PCP).

Further

  • See also differential diagnoses under hyperthermia (overheating).