Herpes Simplex Virus: Or something else? Differential Diagnosis

Skin and subcutaneous (L00-L99).

Infectious and parasitic diseases (A00-B99).

  • Infections caused by other pathogens such as varicella zoster or bacteria.
  • Lymphogranuloma venereum – disease transmitted by serotypes L1-L3 of the bacterial species Chlamydia trachomatis and belongs to the sexually transmitted diseases.
  • Primary effect in syphilis: begins as a papule (coarse millet-sized lump); from this arises the ulcus durum ((German: Harter Schanker, obsolete also Chanker); this has a sharp separated wall-like edge and slightly sunken center
  • Ulcus molle – disease caused by the bacterium Haemophilus ducreyi (gram-negative rods) and belongs to the sexually transmitted diseases.

Musculoskeletal system and connective tissue (M00-M99).

  • Behçet’s disease (synonym: Adamantiades-Behçet’s disease; Behçet’s disease; Behçet’s aphthae) – multisystem disease of the rheumatic type associated with recurrent, chronic vasculitis (vascular inflammation) of the small and large arteries and mucosal inflammation; The triad (the occurrence of three symptoms) of aphthae (painful, erosive mucosal lesions) in the mouth and aphthous genital ulcers (ulcers in the genital region), as well as uveitis (inflammation of the middle eye skin, which consists of the choroid (choroid), the corpus ciliary (corpus ciliare) and the iris) is stated as typical for the disease; a defect in cellular immunity is suspected

Further

  • Autoimmune and bullous diseases (bullous = “associated with blistering”).
  • Bullous sting reactions

Note: For details on differential diagnoses of herpes labialis or genital herpes, see the disease of the same name.