High-dose vitamin D – when useful, when dangerous?

What is vitamin D?

Vitamin D is a generic term for the so-called calciferols – these are fat-soluble vitamins. Their most important representatives are the vitamins D3 and D2. Vitamin D is of particular importance in connection with our bone metabolism – because it helps to ensure that the important minerals calcium and phosphate are absorbed from the intestine and can be incorporated into the bone.

Normally, our body also forms sufficient vitamin D when there is sufficient UV-B radiation. In Germany, however, this is only the case from March to October due to its geographical location. What about the time in between?

Well, usually we are able to produce enough vitamin D during the “sunny period” so that we have a decent store for the “shady days”. But there are other factors that determine whether we are even capable of building up enough reserves. These include : Climate Altitude Air pollution Duration of sunshine Diseases of the stomach, intestines, liver, kidneys Medicine intake (e.g.

certain epilepsy and cancer drugs) Clothing habits (e.g. veiled for religious reasons)

  • Climate
  • Altitude
  • Air Pollution
  • Duration of sunshine
  • Diseases of stomach, intestine, liver, kidneys
  • Taking medication (e.g. certain epilepsy and cancer drugs)
  • Clothing habits (e.g. veiled for religious reasons)

What is high-dose vitamin D therapy?

There is no general answer to this question, as there is no consensus in research on when to speak of high-dose therapy. However, the quantities always have in common that they exceed the quantity of 800 i recommended by the Federal Office for Risk Assessment as the maximum daily intake. E. (international units) recommended by the Federal Office for Risk Assessment.

The concept of high-dose therapy with vitamin D became known primarily through the Brazilian physician Cicero Galli Coimbra and the Coimbra protocol named after him. This protocol is mainly used in multiple sclerosis and provides for doses of sometimes 80,000 i. E. vitamin D per day. The assumption behind it: People suffering from multiple sclerosis are resistant to vitamin D. In addition to the extreme amounts of vitamin D, treated persons receive various micronutrients, must stick to a low-calcium diet, drink plenty of water and exercise frequently.

Problematic: Studies have not been able to prove the benefits of this form of therapy to date – the successes are based to date only on reports of experience. Important: This form of therapy is medically supervised and should by no means be carried out on your own authority. In general, such high-dose therapies can therefore be viewed with scepticism. In the following, we will briefly highlight the benefits of high-dose vitamin D for various diseases.