Hyperthyroidism (Overactive Thyroid): Or something else? Differential Diagnosis

Endocrine, nutritional, and metabolic diseases (E00-E90).

  • Autoimmune thyroiditis (Hashimoto’s thyroiditis) – autoimmune disease of the thyroid gland; initially with increased secretion of thyroid hormones, later with gradual transition to hypothyroidism (hypothyroidism).
  • Hyperthyroidism with decreased or absent uptake in the thyroid scintigram.
  • Hyperthyroidism factitia – overdose of thyroid hormones.
  • Marine-Lenhart syndrome – simultaneous occurrence of nodular goiter with or without autonomy and immunogenic hyperthyroidism (Graves’ disease) denoted.
  • Post-partum thyroiditis – thyroiditis after childbirth.
  • Postradiogenic hyperthyroidism (hyperthyroidism after radiation therapy.
  • Pregnancy hyperthyroidism / gestational hyperthyroidism.
  • Goiter with hyperthyroidism (hyperthyroidism):
    • Initial stage of thyroiditis (with transient hyperthyroid phase).
    • Autonomous (independent) thyroid adenoma / thyroid autonomy (unifocal, multifocal, disseminated, unifocal with disseminated portions).
    • Graves’ disease (immune hyperthyroidism; autoimmune disease of the thyroid gland).
  • Thyroiditis de Quervain (subacute granulomatous thyroiditis) – relatively rare form of thyroiditis, which often occurs after a respiratory infection; circa five percent of all thyroiditis.

Cardiovascular system (I00-I99).

  • Elephantiasis – massive doughy swellings of body parts (e.g., legs) due to chronic congestion of lymphatic fluid.
  • Sinus vein thrombosis (SVT) – occlusion of a cerebral sinus (large venous blood vessels of the brain arising from duraduplications) by a thrombus (blood clot); clinical picture: headache, congestion papules and epileptic seizures [in thyrotoxic crisis because of neurological symptoms].

Infectious and parasitic diseases (A00-B99).

  • Elephantiasis – massive doughy swellings of body parts (e.g., legs) due to chronic congestion of lymphatic fluid.
  • Sepsis (blood poisoning) [in thyrotoxic crisis due tofever > 41 °C]

Neoplasms – tumor diseases (C00-D48).

Psyche – nervous system (F00-F99; G00-G99)

  • Depression
  • Mania
  • Panic attacks

Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).

Medication

  • Medication see below “Causes”)

Environmental pollution – intoxications (poisoning).