Hypertriglyceridemia: Test and Diagnosis

1st order laboratory parameters – obligatory laboratory tests.

Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.

  • Pancreatic parameters – amylase, elastase (in serum and stool), lipase.
  • Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT).
  • Cholesterol electrophoresis
  • Apolipoprotein E
  • Apolipoprotein A1 (APOA1) – risk assessment for the development of atherosclerosis (arteriosclerosis, hardening of the arteries).
  • Apolipoprotein B (APOB) – risk assessment for the development of atherosclerosis APO B decreased in:
    • Lipoprotein deficiency, hyperlipoproteinemia type I.

    APO B elevated in:

    • Hyperlipoproteinemias type II, III, V, pAVK, myocardial infarction.
  • Lipoprotein (a)
  • Homocysteine (independent risk factor for cardiovascular disease).
  • DNA analyses in suspected genetic causes such as familial hypercholesterolemia (FH) or familial hypertriglyceridemia.
  • Family screening in familial hypercholesterolemia.
    • Blood lipids of parents and first-degree relatives should be screened