Ibuprofen | NSAR – non-steroidal anti-inflammatory drugs

Ibuprofen

Ibuprofen is also one of the non-steroidal anti-inflammatory drugs and belongs together with ketoprofen and naproxen to the group of arylpropionic acids. Non-steroidal means that the drugs do not contain cortisone. It is used for mild to moderate, acute and chronic pain, and chronic inflammatory diseases.

Ibuprofen is especially helpful for toothache, migraine, back pain and menstrual pain. As it is a non-steroidal anti-inflammatory drug, it can cause side effects in the gastrointestinal tract or asthmatic complaints (see section above). However, ibuprofen in particular causes side effects on the kidneys, so ibuprofen should never be taken by people with kidney failure or by people who have had a kidney transplant.

The maximum daily dose is 1200 mg or 1.2 g. In addition, this maximum daily dose should not be taken for more than three to five days without consulting a doctor.Ibuprofen is available from various companies under several trade names, for example Hexal, Ratiopharm or Johnson & Johnson GmbH. The most common dosages are 400 mg, 600 mg or 800 mg ibuprofen per tablet. There are also preparations that additionally contain lysine, an amino acid.

These are 400 mg tablets to which lysine is added. The amino acid accelerates the absorption of ibuprofen into the body, which results in a faster onset of action after as little as 20-30 minutes. Ibuprofen 400 mg can be bought over the counter in pharmacies, while 600 mg and 800 mg tablets require a prescription from a doctor. Ibuprofen is sold only in pharmacies and cannot be bought in drugstores or similar stores. The Proff® Pain Cream contains ibuprofen as the active ingredient.

Interactions

Cortisone cortisone: anticoagulant:

  • With simultaneous Kortisongabe the bleeding risk in the gastro-intestinal tract rises substantially
  • NSAID ́s should not be given concomitantly with anticoagulant preparations or preparations of the same class of active ingredients (diclofenacindometacin-piroxicam-ibuprofen). In particular with the simultaneous administration of Marcumar should be considered, which strengthens the blood-thinning effect of Marcumar.