Idarubicin

Products

Idarubicin is commercially available in capsule form and as a solution for injection (Zavedos, generics). It has been approved in many countries since 1992.

Structure and properties

Idarubicin (C26H27NO9, Mr = 497.5 g/mol)

Effects

Idarubicin (ATC L01DB06) is a cytotoxic anthracycline antibiotic. It inhibits topoisomerase II by intercalation into DNA, thereby inhibiting nucleic acid and protein synthesis.

Indications

Leukemia