Products
Idarubicin is commercially available in capsule form and as a solution for injection (Zavedos, generics). It has been approved in many countries since 1992.
Structure and properties
Idarubicin (C26H27NO9, Mr = 497.5 g/mol)
Effects
Idarubicin (ATC L01DB06) is a cytotoxic anthracycline antibiotic. It inhibits topoisomerase II by intercalation into DNA, thereby inhibiting nucleic acid and protein synthesis.
Indications
Leukemia