Interactions | Lamotrigine

Interactions

Interactions are defined as the interaction of a drug with other drugs when taken simultaneously. Lamotrigine shows partial interactions with other antiepileptic drugs, which increases the probability of side effects. These include valproate, carbamazepine, phenytoin or phenobarbital.

The administration of risperidone, which is used in mental illness, can also lead to interactions. Some antibiotics or drugs used to treat viral diseases can also interact with lamotrigine. Contraception should also be discussed with the doctor, as the effectiveness of contraception can be altered by interactions.

The effectiveness of the antiepileptic drug may also be affected by the use of hormonal contraceptives, which may require a dose adjustment. Patients who are being treated for epilepsy with medication may be very sensitive to alcohol. As a rule, a responsible, moderate consumption of alcohol is not associated with an increased risk of seizures.

Nevertheless, the effect of alcohol can influence the effect of anticonvulsants, which can be accompanied by an increase in side effects such as double vision, balance disorders, and others.The consumption of large amounts of alcohol can promote the occurrence of epileptic seizures, especially if this causes sleep deprivation or irregular medication. The consumption of alcohol by epilepsy patients should therefore always be carried out in a responsible and controlled manner. Taking the pill can influence the effect of Lamotrigine.

The patient should inform her doctor about the use of hormonal contraceptives and discuss with him alternatives to contraception. Lamotrigine can also influence the effectiveness of the pill, but a decrease in effectiveness seems unlikely so far. However, patients who notice changes in their periods, bleeding between periods or spotting should consult their doctor and use additional contraceptive measures.

When should Lamotrigine not be given?

An allergy is always a contraindication to taking a drug as a possible trigger of a life-threatening anaphylactic reaction. Even in the case of skin abnormalities after taking lamotrigine or other drugs for epilepsy, the utmost caution is required. Caution is advised when taking Lamotrigine in case of existing kidney problems. Patients who are already taking a medication for seizures should inform their doctor about it.