1st order laboratory parameters – obligatory laboratory tests.
- Urine status (rapid test for: pH, leukocytes, nitrite, protein, glucose, blood), sediment.
- Urine cytology – in the case of sterile leukocyturia (excretion of white blood cells with urine without the presence of urinary tract infection) and / or microhematuria (presence of blood in the urine (hematuria), which can be detected microscopically or by means of test strips (Sangur test )).
- Urine and serum markers
- APF (“antiproliferative factor”) – produced in the bladder and found almost exclusively in the urine of people with interstitial cystitis; APF probably blocks the physiological growth of cells of the bladder inner wall
- NGF (“nerve growth factor”/nerve growth factor).
- IL (interleukin)-6 [↑] – regulates inflammatory responses.
- TNF-α (tumor necrosis factor-α) [↑]
- Molecular diagnostics – detection of specific cell proteins.
- Inflammatory parameters – CRP (C-reactive protein) or PCT (procalcitonin).
- Biopsy (tissue sample) of the bladder wall – to detect mast cells [↑]
Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.
- Urine culture (pathogen detection and resistogram (testing of appropriate antibiotics for sensitivity / resistance) – to exclude infectionMan: midstream urine; woman: catheter urine.
- Small blood count
- Fasting glucose (fasting plasma glucose; fasting blood glucose).
- PSA (prostate-specific antigen)
- If necessary, exclusion of a venereal disease (infections transmitted mainly through sexual intercourse) – in cystitis with adnexitis (inflammation of the fallopian tube and ovary), colpitis (vaginitis), prostatitis (prostatitis).