Iron Deficiency Anemia: Medical History

Medical history (history of illness) represents an important component in the diagnosis of iron deficiency anemia.

Family history

  • Are there any diseases in your family that are common?

Social history

  • Is there any evidence of psychosocial stress or strain due to your family situation?

Current medical history/systemic history (somatic and psychological complaints).

  • Have you noticed symptoms such as decreased performance, difficulty concentrating, or fatigue?
  • Have you noticed skin symptoms such as mouth rhagades (lazy mouth), aphthae (painful milky-yellowish formations) on the oral mucosa, or pale skin/mucous membranes?
  • Do you have hair loss or brittle nails?
  • Do you suffer from dry, itchy skin?
  • Have you noticed symptoms such as night sweats, fever or weight loss?* .
  • How long have these symptoms been present? Please indicate chronological order?

Vegetative anamnesis incl. nutritional anamnesis.

  • Do you eat a balanced diet?
  • Are you vegetarian or vegan (lifestyle that rejects the use of animals and animal products)?
  • Do you take enough iron with food?
  • Are you an athlete?
  • Do you donate blood regularly?

Self history including medication history.

  • Pre-existing conditions (gastrointestinal diseases; blood clotting disorders; tumor diseases).
  • Surgeries (gastric surgery)
  • Allergies
  • Pregnancies

Medication history

  • Antiprotozoal drugs
    • Analogue of the azo dye trypan blue (suramin).
    • Pentamidine
  • Chelating agents (D-penicillamine, trieethylenetetramine dihydrochloride (Trien), tetrathiomolybdenum).
  • Direct factor Xa inhibitor (rivaroxaban).
  • Immunosuppressants (thalidomide).
  • Janus kinase inhibitors (ruxolitinib).
  • Monoclonal antibodies – pertuzumab
  • MTOR inhibitors (everolimus, temsirolimus).
  • Neomycin
  • P-aminosalicylic acid (mesalazine)
  • Proton pump inhibitors (PPI; acid blockers) – patients on continuous PPI therapy are more often affected by iron deficiency: this depends on therapy duration and dosage
  • Thrombin inhibitor (dabigatran).
  • Tuberculostatics (isoniazid, INH; rifampicin, RMF).
  • Antivirals

* If this question has been answered with “Yes”, an immediate visit to the doctor is required! (Data without guarantee)