Products
Isopropanol is available as a pure substance in pharmacies and drugstores. A common aqueous dilution is 70% (V/V). WHO has published a manufacturing specification of 75% (V/V) for hand disinfection, which also contains glycerol and hydrogen peroxide. Isopropanol is also known as isopropy alcohol or alcohol isopropylicus, and the systematic name is propan-2-ol.
Structure and properties
Isopropanol (C3H8O, Mr = 60.1 g/mol) is a secondary alcohol. It is formally propane with a hydroxyl group at position 2. Isopropanol is non-chiral and exists as a clear, colorless liquid with a typical “medicinal” odor that is miscible with water and ethanol 96%. The boiling point is > 80°C. Isopropanol can be oxidized to the corresponding ketone acetone.
Areas of application
Fields of application of isopropanol (selection):
- Propan-1-ol and propan-2-ol are contained in numerous disinfectants, for example, for surface disinfection, skin disinfection and hygienic and surgical hand disinfection (70% or 75% V/V).
- As an excipient, for example, in diclofenac gels.
- In dipping drops for the prevention of otitis externa.
- As a reagent and as a solvent.
- As a cleaning agent.
Dosage
For hygienic hand disinfection, the liquid is rubbed well on the hands during at least 30 seconds. The hands should remain moist throughout the duration. Allow to air dry.
Adverse effects
Isopropanol and its vapors are highly flammable and should not be exposed to flames or sources of ignition. The liquid may cause severe eye irritation, drowsiness and dizziness. The appropriate precautions must be observed. Isopropanol should not be ingested.
