Knee Osteoarthritis (Gonarthrosis): Cartilage-Protective Agents (Chondroprotectants)

Chondroprotectants inhibit cartilage-degrading substances and thus reduce further loss of protective cartilage. At the same time, they promote the regeneration of cartilage tissue.Furthermore, they are believed to have an anti-inflammatory effect. As a result, there is a reduction in pain, swelling and improved joint mobility. The greatest success is achieved by injecting chondroprotectants directly into the damaged joint.

The following agents are considered chondroprotectants and are used in therapy:

  • Chondroitin sulfate
  • Glucosamine sulfate
  • Hyaluronic acid
  • Oxaceprol
  • Vitamin E
  • Ademethionine (S-adenosylmethionine, SAM)

The above vital substance (micronutrient) recommendations were created with the help of medical experts. The statements are supported by evidence-based medicine literature, which means clinical studies with a high degree of effectiveness.