Products
Labetalol is commercially available in tablet form and as a solution for injection (Trandate). It has been approved in many countries since 1978.
Structure and properties
Labetalol (C19H24N2 O3, Mr = 328.4 g/mol) is present in drugs as labetalol hydrochloride, a white powder that is sparingly soluble in water.
Effects
Labetalol (ATC C07AG01) has antihypertensive properties. It is a beta-blocker with additional alpha-blocking activity.
Indications
For the treatment of hypertension (high blood pressure).
Dosage
According to the professional information leaflet. The tablets are usually administered two to three times daily after meals. The solution for injection is intended for rapid lowering of blood pressure and is injected or infused slowly intravenously.
Contraindications
For complete precautions, see the drug label.
Adverse effects
The most common possible adverse effects include increased liver function values, congestive heart failure, lethargy, erectile dysfunction, urinary discomfort, nausea, low blood pressure, visual disturbances, nasal congestion, and hypersensitivity reactions.
