Leprosy: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate leprosy:

Symptoms of indeterminate leprosy

  • Small hypopigmented spots (macules) – heal spontaneously in circa 75% of cases.

Symptoms of tuberculoid leprosy

  • Few sharply demarcated hypopigmented skin lesions with raised marginal ridge, central healing if necessary.
  • Hypesthesia/hypoesthesia to anesthesia (decreased pain sensitivity/painlessness) in the affected area.
  • Disturbed sweat secretion
  • Nerve thickening
  • Sensory disturbances
  • Paralysis
  • Keratomalacia (softening of the cornea)

Symptoms of lepromatous leprosy

  • Skin nodules (lepromatous), prone to severe enlargement and ulceration (ulceration), especially on the trunk and face.
  • Facies leontina (lion-like face).
  • Madarosis – loss of eyebrows and eyelashes.
  • Loosening of the front incisors (Möller-Christensen phenomenon).
  • Saddle nose
  • Rough voice
  • Alopecia (hair loss)
  • Impaired sweat secretion
  • Sensory loss
  • Paralyses
  • Disturbance of autonomic innervation
  • Glomerulonephritis (inflammation of the renal corpuscles).
  • Amyloidosis – systemic disease with deposits of proteins (protein) in various organ systems.

Overall, there is always a gradual onset of symptoms.

Furthermore, in the course of the disease is a settlement in all organs possible.