1st order
- Ascites puncture (abdominal fluid aspiration) – in cases of high-grade thrombocytopenia (deficiency of platelets (thrombocytes): < 20. 000/μl), a prophylactic platelet transfusion is performed before the puncture; anticoagulation (anticoagulation) with acetylsalicylic acid can be continued – on the other hand, a break must be taken in the case of therapy with thienopyridines or glycoprotein IIb/IIIa inhibitors as well as vitamin K antagonists and direct oral anticoagulants (DOAK); in the case of high urgency of the procedure, e. g. For example, in cases of suspected spontaneous bacterial peritonitis (SBP; infection of the ascites), ascites puncture may be performed without discontinuation of anticoagulants.
- Liver transplantation (LTx) – implantation of a foreign organ; however, it is indicated only when cirrhosis decompensates, that is, when liver dysfunction can no longer be adequately compensated; it is the only curative therapy for cirrhosis and is the most common indication for liver transplantation in Europe (52%).
- Non-alcoholic fatty liver disease (NASH; non-alcoholic steatohepatitis) is now one of the most common indications for liver transplantation.
