In patients with localized nodes and a benign clinical picture, an observation period of three to four weeks is advisable. Generalized adenopathy should always prompt further clinical investigation.
Lymph nodes are considered abnormal:
- Adult patients: > 1 cm (inguinal: > 1.5 cm).
- Children: lymph node enlargements up to 2 cm often do not require further clarification, as they are mostly of reactive genesis.
Notes on lymph node biopsy:
- Extirpation (removal) of the largest and most accessible lymph node, preferring cervical (neck region) and supraclavicular (above the collarbone) lymph nodes.
- Caution: axillary (armpit) lymph nodes are more difficult to access surgically and biopsy is often fraught with complications
- Inguinal (groin region) and submandibular (below the lower jaw) lymph nodes are often altered for inflammation
In addition to histological examination, if necessary, microbiological examination (eg, if TB is suspected).
