1st order laboratory parameters – obligatory laboratory tests.
- Microscopic of the bacterial species Chlamydia trachomatis by immunofluorescence.
- Detection of serotypes L1-L3 of the bacterial species Chlamydia trachomatis [acute LGV infection fourfold increase in antibody titers; CFT > 1:64, MIFT > 1:128].
- DNA detection of Chlamydia trachomatis by “nucleic acid amplification tests” (NAAT) (gold standard; sensitivity of circa 90% and a specificity of 100%.
- HIV test (in the case of unknown HIV status).
Examination material: vesicle contents of the primary lesion; ulcer material of anogenital lesions, smears (genital or rectal), rectal biopsies in case of anorectal involvement, lymph node aspirate.
2nd order laboratory parameters – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification
- Bacteria
- Neisseria gonorrhoeae (gonorrhea, gonorrhea) – genital swab for pathogen and resistance, specifically for Neisseria gonorrhoeae.
- Treponema pallidum (syphilis, lues) – antibodies against Treponema pallidum (TPHA, VDRL, etc.).
- Ureaplasma urealyticum
- Viruses
- HIV (AIDS)
- Herpes simplex virus type 1/2 (HSV type 1 u. 2)
- Mycoses / parasites
- Candida albicans a.o. Candida species genital smear – pathogen and resistance).
- Trichomonas vaginalis (trichomoniasis, colpitis) – antigen detection.
