Macrocytosis: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps:

  • General physical examination – including blood pressure, pulse, body weight, height; further:
    • Inspection (viewing): skin, mucous membranes, and sclerae (white part of the eye) [jaundice (yellowing of the skin)?, smooth red tongue?, cheilosis (redness and swelling of the lips)?, glossitis (inflammation of the tongue)?]
    • Auscultation (listening) of the heart.
    • Palpation (palpation) of the abdomen (abdomen) (pressure pain?, knock pain?, release pain?, cough pain?, defensive tension?, hernial orifices?, kidney bearing knock pain?)
  • Cancer screening
  • Neurological examination – including assessment of reflex activity and sensitivity [due topossible sequelae: Ataxia (gait disturbances), dementia, impaired sensation of position, impaired sensation of vibration, muscle weakness, paresis (paralysis) in extremities, psychosis, numbness in extremities, forgetfulness, decreased or increased reflexes]
  • Health check

Square brackets [ ] indicate possible pathological (pathological) physical findings.