Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99).
- Klinefelter syndrome – genetic disorder with mostly sporadic inheritance: numerical chromosomal aberration (aneuploidy) of the sex chromosomes (gonosomal anomaly) occurring only in boys or Men occurs; in the majority of cases characterized by a supernumerary X chromosome (47, XXY); clinical picture: large stature and testicular hypoplasia (small testis), caused by hypogonadotropic hypogonadism (gonadal hypofunction); usually spontaneous onset of puberty, but poor pubertal progress.
- Cryptorchidism – absent testis, incomplete testicular descent (inguinal testis, sliding testis, pendulous testis, testicular ectopy).
Endocrine, nutritional and metabolic diseases (E00-E90).
- Hemochromatosis (iron storage disease) – genetic disease with autosomal recessive inheritance with increased deposition of iron as a result of increased iron concentration in the blood with tissue damage.
- Hypergonadotropic hypogonadism (gonadal hypofunction associated with increased gonadotropins) due to testicular damage (testicular damage)
- Hypogonadotropic hypogonadism (gonadal hypofunction associated with decreased gonadotropins; e.g., Kallmann syndrome; idiopathic).
- Hyperprolactinemia – unphysiological increase in prolactin levels.
- Kallmann syndrome (synonym: olfactogenital syndrome): genetic disorder that can occur sporadically, as well as be inherited in an autosomal dominant, autosomal recessive, and X-linked recessive manner; symptom complex of hypo- or Anosmia (decreased to absent sense of smell) in conjunction with testicular or ovarian hypoplasia (defective development of the testis or ovaries, respectively); prevalence (disease frequency) in males 1: 10,000 and in females 1: 50,000.
Infectious and parasitic diseases (A00-B99).
- HIV infection in childhood
Psyche – nervous system (F00-F99; G00-G99).
- Substance abuse
- Brain lesions in the area of the sella turcica – bony region where the pituitary gland (pituitary gland) is located
Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99).
- Infectious orchitis in childhood (testicular inflammation).
Injuries, poisonings, and other sequelae of external causes (S00-T98).
- Irradiation in childhood for the treatment of cancer.
- Chemotherapy in childhood for the therapy of cancers.
- Condition after orchiectomy (testicular removal).
Further
- Excessive endurance sports
