The following are the major diseases or complications that may be contributed to by malignant fibrous histiocytoma (MFH):
Neoplasms – Tumor Diseases (C00-D48).
- Metastasis (daughter tumors) – especially pulmonary (“to the lungs”; 90%), rarely osseous (“to the bones“; 8%) or hepatogenous (“to the liver“; 1%).
Psyche – Nervous System (F00-F99; G00-G99).
- Depression
Further
- Functional disorders of the affected organ (organ insufficiency).
Prognostic factors
Prognostically unfavorable parameters are:
- Tumor size > 5 cm
- Higher age of the patient
- Proximal (towards the center of the body/near the trunk) and deep localization of the tumor.
- High histological grade – a distinction is made between low-, intermediate- and high-grade.
- Metastasis (formation of daughter tumors).
