Malignant Fibrous Histiocytoma: Drug Therapy

Therapeutic targets

• Removal of the tumor – see “Surgical therapy“.
• Healing

Therapy recommendations

• Analgesia according to WHO staging scheme:
  • Non-opioid analgesic (paracetamol, first-line agent).
  • Low-potency opioid analgesic (e.g., tramadol) + non-opioid analgesic.
  • High-potency opioid analgesic (eg, morphine) + non-opioid analgesic.
• Malignant fibrous histiocytoma is not very sensitive to radiation. Nevertheless, postoperative radiotherapy (radiotherapy) reduces the formation of local recurrence (recurrence of the disease).
• If necessary, chemotherapy