1st order laboratory parameters – obligatory laboratory tests.
- Biopsy (tissue sample) – characteristic of malignant fibrous histiocytoma is pleomorphy (nuclei of similar cells take on a different appearance): the cells resemble a fibroblast (connective tissue cell) on the one hand and a histiocyte (resident phagocyte) on the other.
Caveat: Because other sarcomas also contain pleomorphic variants, confusion can occur, so the diagnosis of “malignant fibrous histiocytoma” is often a diagnosis of exclusion.
