Malignant Melanoma: Medical History

Medical history (history) represents an important component in the diagnosis of malignant melanoma (MM).

Family history

  • Are there frequent tumors of the skin in your family?

Social anamnesis

Current medical history/systemic history (somatic and psychological complaints).

  • What changes have you noticed?
  • Have any individual nevi changed in shape, color, or texture?
  • Do these skin lesions tend to bleed or crust?
  • Do these skin lesions grow very quickly?
  • How long have these changes existed?
  • Where do you have these changes (chest, back, extremities, etc.)?

Vegetative history including nutritional history.

  • Are you/were you frequently exposed to intense UV radiation? (Sunbathing / sunbeds)
  • Are you overweight? Please tell us your body weight (in kg) and height (in cm).

Self anamnesis incl. medication anamnesis

  • Pre-existing conditions (skin diseases; hypertension).
  • Operations
  • Allergies
  • Medication history
    • Angiotensin receptor blockers (possibly due tophotosensitizing effect).
    • Hydrochlorothiazide (HTC) – increased risk of developing nodular or lentiginous melanoma).
    • Sildenafil (PDE-5 inhibitor).
  • Environmental history (radon; UV light;
    • Herbicides (for occupational exposure; risk increase approximately 85% for any exposure; no significant risk increase, however, over insecticides or pesticides) Note: risk of bias from UV radiation).