Manganese: Symptoms of Deficiency

Signs of manganese deficiency as observed in experimental animals – include retarded or slowed growth, poor sexual or reproductive function, abnormalities of the bony skeleton, impaired glucose tolerance, and impaired lipid metabolism.

To date, no deficiency symptoms have been observed in humans that could be clearly attributed to a manganese deficiency.
For the Federal Republic of Germany, there is no evidence of an inadequate supply status of manganese, i.e., manganese deficiency states have not become known in the German population.[1]

Manganese deficiency is not expected in humans because of its ubiquitous occurrence.

Literature

1. Bundesinstitut für RisikobewertungVerwendung von Mineralstoffen in Lebensmitteln Toxikologische und ernährungsphysiologische AspekteA. Domke, R. Großklaus, B. Niemann, H. Przyrembel, K. Richter, E. Schmidt, A. Weißenborn, B. Wörner, R. Ziegenhagen (eds.), ch. 16, pp. 293-299,BfR-Wissenschaft 04/2004, Berlin (2004).
2. Biesalski, H. K.; Köhrle, J.; Schümann, K., ch. 33, pages 233-234,
   In: Vitamins, trace elements and minerals.
   Georg Thieme Verlag; Stuttgart/New York 2002.