Products
In many countries, finished drug products containing meclofenamic acid are currently no longer available. Meclomen capsules are out of stock.
Structure and properties
Meclofenamic acid (C14H11Cl2NO2, Mr = 296.1 g/mol) belongs to the anthranilic acid derivatives. It is structurally related to mefenamic acid (Ponstan, generics) and is present in drugs as meclofenamate sodium, a white, almost odorless, crystalline powder that is highly soluble in water.
Effects
Meclofenamic acid (ATC M01AG04) has analgesic, anti-inflammatory, and antipyretic properties. The effects are due to inhibition of the enzyme cyclooxygenase (COX) and thus the synthesis of prostaglandins.
Indications
For the treatment of pain, fever, and inflammatory disorders.