Meningococcal Sepsis: Test and Diagnosis

1st order laboratory parameters – obligatory laboratory tests.

  • Small blood count
  • Inflammatory parameters – CRP (C-reactive protein) and PCT (procalcitonin).
  • Fasting glucose (fasting blood glucose).
  • Blood gas analysis (BGA)
  • Thyroid parameters – TSH
  • Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT).
  • Renal parameters – creatinine, urea.
  • Coagulation parameters – PTT, Quick
  • CSF puncture (collection of cerebrospinal fluid by puncture of the spinal canal) for CSF diagnostics – for cultivation and biochemical differentiation for the detection of Neisseria meningitidis* .
  • Blood cultures*

* In particular, the suspected disease, the disease as well as death from meningococcal meningitis or sepsis must be reported in the sense of the Infection Protection Act.2nd order laboratory parameters – depending on the results of the medical history, the physical examination and the obligatory laboratory parameters – for differential diagnostic clarification.

  • Interleukin-6 (IL-6), tumor necrosis factor (synonyms: TNF α, cachectin, lymphotoxin), or lipopolysaccharide-binding protein-laboratory parameters that may indicate sepsis at an early stage.