Mevastatin

Products

Mevastatin has never been marketed but has played an important role in the development of statins.

Structure and properties

Mevastatin (C23H34O5, Mr = 390.5 g/mol), the first statin, was identified as a natural product in 1973 at the Japanese pharmaceutical company Sanyko by Akira Endo during screening of thousands of mushroom extracts from.

Effects

Mevastatin is lipid-lowering; see under statins.