Mexiletin

Products

Mexiletine is commercially available in the form of capsules. No drugs containing the active ingredient are currently registered in many countries.

Structure and properties

Mexiletine (C₁₁H₁₇NO, M_r = 179.3 g/mol) is present in drugs as mexiletine hydrochloride, a white, crystalline powder with a slightly bitter taste that is readily soluble in water. It is structurally related to lidocaine but can be administered perorally.

Effects

Mexiletine (ATC C01BB02) has antiarrhythmic and local anesthetic properties. The effects are due to inhibition of sodium channels.

Indications

For the treatment of cardiac arrhythmias.