Laboratory parameters of 1st order – obligatory laboratory tests.
- Small blood count
- Inflammatory parameters – CRP (C-reactive protein).
- Urinalysis
- Microscopy (microhematuria/excretion of blood in urine not visible to the naked eye).
- Proteinuria (increased excretion of protein in the urine).
- Autoimmune serology
- PANCA (perinuclear antineutrophil cytoplasmic antibody); often with the target antigen myeloperoxidase (anti-myeloperoxidase antibody/MPO-ANCA) (in 60% of cases)Note: Histological confirmation of the diagnosis by biopsy of clinically affected organs should be sought.
- Renal parameters – urea, creatinine, cystatin C or creatinine clearance if necessary.
- Biopsy (tissue sample) of the kidneys – to detect glomerulonephritis.
