Mold Allergy: Secondary Diseases

The following are the most important diseases or complications that may be contributed to by mold allergy:

Respiratory system (J00-J99)

  • Allergic rhinitis (allergic rhinitis).
  • Allergic rhinoconjunctivitis – allergy-related disease of the nasal mucosa (rhinitis) and conjunctiva of the eyes (conjunctivitis) [type I allergy].
  • Allergic bronchopulmonary aspergillosis (ABPA) – mixed allergic disease of the lung triggered by molds of the tubular fungus genus Aspergillus; characterized by high total IgE levels (> 1,000 IU/ml), pulmonary infiltrates (inflammatory process in the lungs), and central bronchiectasis (irreversible saccular or cylindrical dilatation of the bronchi (medium-sized airways)) [Type I and Type III allergy]Occurrence: Patients with cystic fibrosis or cystic fibrosis (10-15%), asthmatics (1%).
  • Bronchial asthma [type I allergy]
  • Chronic sinusitis (sinusitis) or chronic rhinosinusitis (CRS; simultaneous inflammation of the nasal mucosa (“rhinitis”) and the mucosa of the paranasal sinuses (“sinusitis“)).
  • Tracheitis allergica – tracheitis associated with severe coughing attacks.

Skin and subcutaneous (L00-L99)

  • Allergic eczema (inflammatory change of the skin).
  • Urticaria – disease characterized by edematous efflorescences [type I allergy].

Mouth, esophagus (food pipe), stomach, and intestines (K00-K67; K90-K93).

Injuries, poisonings, and other sequelae of external causes (S00-T98).

  • Anaphylactic reaction

Prognostic factors

  • Sensitization to Alternaria alternata is bes. described as a risk factor for the development, persistence, and worsening of bronchial asthma.