Morclofon

Products

Morclofon is commercially available as a syrup (Nitux). It has been approved in many countries since 1979.

Structure and properties

Morclofon (C21H24ClNO5, Mr = 405.87 g/mol) is 4′-chloro-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenone.

Effects

Morclofon (ATC R05DB25) has central antitussive and bronchospasmolytic properties. It is an older drug. Modern registration studies are lacking.

Indications

For the treatment of irritable cough of various origins.

Dosage

According to the professional information. The syrup is taken between two to six times a day after meals, depending on age. For infants up to 6 months of age, a doctor’s prescription is required.

Contraindications

  • Hypersensitivity
  • Pregnancy and lactation
  • Infants up to 6 months of age should be administered Morclofon only under medical supervision.

Full precautions can be found in the drug label.

Interactions

No information is available on drug-drug interactions.

Adverse effects

Possible adverse effects include indigestion, headache, drowsiness, and dullness.