Products
MSM is commercially available in the form of tablets, capsules and powder, among others, as a food supplement without indications. It is also applied externally, for example, as a cream and balm. Medicines containing MSM have not yet been approved.
Structure and properties
MSM (C2H6O2S, Mr = 94.1 g/mol) is a low molecular weight organic sulfur compound. It is a natural substance found, for example, in the environment, fruits, vegetables, grains, coffee, milk, and also in the human body. MSM is present as a white, odorless and slightly bitter tasting crystalline powder. It is also formed in the organism from DMSO and is therefore also called DMSO2. Unlike DMSO, it has a high melting point of 109°C – DMSO melts even at room temperature.
Effects
MSM has anti-inflammatory, antioxidant, immunomodulatory, and antitumor properties. It is also known as a sulfur donor.
Fields of application
Possible indications for use include joint disease, osteoarthritis, rheumatoid arthritis, inflammatory diseases, and allergic rhinitis (selection). MSM is mainly used in complementary medicine. In our view, the clinical data are still insufficient.
Dosage
According to the package insert. Use depends on the product.
Contraindications
We do not have complete information.
Adverse effects
MSM is considered well tolerated at prescribed doses. However, complete data are not available to us.
