Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99).
- Alport syndrome (also called progressive hereditary nephritis) – genetic disorder with both autosomal dominant and autosomal recessive inheritance with malformed collagen fibers that can lead to nephritis (inflammation of the kidneys) with progressive renal failure (kidney weakness), sensorineural hearing loss, and various eye diseases such as a cataract (cataract)
- Osteoonychodysplasia (synonyms: hereditary onychoosteodysplasia, Turner-Kieser syndrome, Trauner-Rieger syndrome, nail-patella syndrome) – genetic disease with both autosomal dominant inheritance associated with various malformations and organ dysfunction; subcomplex associated with deformities of the fingernails and bones is also called nail-patella syndrome; furthermore, organic disorders such as renal insufficiency (affects 50% of affected patients).
Blood, blood-forming organs – immune system (D50-D90).
- Sarcoidosis (synonyms: Boeck’s disease; Schaumann-Besnier’s disease) – systemic disease of connective tissue with granuloma formation.
Endocrine, nutritional and metabolic diseases (E00-E90).
- Amyloidosis – extracellular (“outside the cell”) deposits of amyloids (degradation-resistant proteins) that can lead to cardiomyopathy (heart muscle disease), neuropathy (peripheral nervous system disease), and hepatomegaly (liver enlargement), among other conditions.
Circulatory system (I00-I99)
- Cardiomyopathy, congestive
- Renal vein thrombosis – vascular disease in which a blood clot (thrombus) has formed in the renal vein (renal vein).
Liver, gallbladder and bile ducts – pancreas (pancreas) (K70-K77; K80-K87).
- Cirrhosis of the liver – damage to the liver and a marked remodeling of liver tissue. It is the endpoint of many liver diseases, characterized by a slowly progressive (advancing) course over decades
Musculoskeletal system and connective tissue (M00-M99).
- Granulomatosis with polyangiitis (GPA; formerly Wegener’s granulomatosis) – necrotizing (tissue dying) vasculitis (vascular inflammation) of the small to medium-sized vessels (small-vessel vasculitides), which is associated with granuloma formation (nodule formation) in the upper respiratory tract (nose, sinuses, middle ear, oropharynx) as well as the lower respiratory tract (lungs)
- Lupus erythematosus – group of autoimmune diseases in which there is the formation of autoantibodies; belongs to the collagenoses.
Neoplasms – tumor diseases (C00-D48).
- Hodgkin’s disease – malignant neoplasm (malignant neoplasm) of the lymphatic system with possible involvement of other organs.
- Plasmocytoma (multiple myeloma) – systemic disease; belongs to the non-Hodgkin’s lymphomas of B lymphocytes. Multiple myeloma is associated with malignant (malignant) neoplasm of plasma cells and the formation of paraproteins
Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99).
- Acute interstitial nephritis – form of inflammation of the kidneys.
- C1q nephropathy – rare form of inflammation of the renal corpuscles that occurs primarily in children and young adults
- Diabetic nephropathy – form of kidney disease caused by diabetes.
- Glomerulonephritis (inflammation of the renal corpuscles).
- Membranous glomerulonephritis [primary or secondary to hepatitis B or C].
- Membranoproliferative glomerulonephritis (MPGN).
- Minimal change glomerulonephritis (MCGN)
- Glomerulosclerosis – transformation of the renal corpuscles that can occur due to numerous diseases.
- Purpura-Schoenlein-Henoch nephritis – nephritis (inflammation of the kidneys) that, in severe cases, leads to chronic renal insufficiency and requires permanent renal replacement therapy
