Oligomenorrhea: Or something else? Differential Diagnosis

Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99).

  • Laurence-Moon-Biedl-Bardet syndrome (LMBBS) – rare genetic disorder with autosomal recessive inheritance; differentiated by clinical symptoms into:
    • Laurence-Moon syndrome (without polydactyly, i.e., without the appearance of supernumerary fingers or toes, and obesity, but with paraplegia (paraplegia) and muscle hypotonia/reduced muscle tone) and
    • Bardet-Biedl syndrome (with polydactyly, obesity and peculiarities of the kidneys).

Endocrine, nutritional and metabolic diseases (E00-E90).

  • Hyperandrogenemia (elevation of male sex hormones in the blood).
  • Hyperprolactinemia (increase in prolactin levels in the blood).
  • Hypothyroidism (hypothyroidism) or latent (subclinical/mild) hypothyroidism.
  • Ovarian hypoplasia – underdevelopment of the ovaries due to various diseases such as Turner syndrome (gonadal dysgenesis).
  • Polycystic ovary syndrome (PCO syndrome) – cyst formation in the ovary, which leads to impaired hormonal function.
  • Sheehan syndrome – postpartum (after childbirth) anterior pituitary insufficiency (HVL insufficiency; insufficient hormone production by the anterior lobe of the pituitary gland (pituitary gland)).
  • Premature ovarian failure – ovarian function depletion with progressive follicular atresia (failure to produce follicles).

Neoplasms – tumor diseases (C00-D48).

Psyche – nervous system (F00-F99; G00-G99)

  • Anorexia nervosa (anorexia nervosa)
  • Psychogenic reaction such as after severe personal or other disasters.

Medication

  • Appetite suppressants – such as fenfluramine.
  • Hormonal contraceptives (contraception using preparations containing estrogen and/or progestin); post-pill amenorrhea – absence of menstruation after stopping the use of contraceptives (contraceptives)
  • See also under “Hyperprolactinemia due to medications.”
  • Zust. n. chemotherapy

Drugs

  • Amphetamines (indirect sympathomimetic).
  • Heroin
  • LSD (lysergic acid diethylamide)

Other causes

  • Competitive sports
  • Gravidity (pregnancy)
  • Lactation period (breastfeeding phase)
  • Zust. n. Radiatio (radiotherapy)