Osteoarthritis: Or something else? Differential Diagnosis

Differential diagnoses for coxarthrosis (osteoarthritis of the hip joint)

Cardiovascular (I00-I99).

  • Peripheral arterial occlusive disease (pAVD) – progressive narrowing or occlusion of the arteries supplying the arms/ (more commonly) legs, usually due to atherosclerosis (arteriosclerosis, hardening of the arteries)

Mouth, esophagus (esophagus), stomach and intestines (K00-K67; K90-K93).

Musculoskeletal system and connective tissue (M00-M99)

  • Arthritis (inflammation of the joints) – this is characterized by inflammatory changes that start in the joint capsule as synovitis (inflammation of the synovial membrane).
  • Bacterial arthritis (infection of the joints).
  • Bursitis (inflammation of the bursa)
  • Femoral head necrosis – tissue death due to lack of blood supply to the femoral head.
  • Insertion tendinopathy – due to irritation at the junction between tendons and bones, i.e. pain conditions arising in the area of insertion.
  • Osteoporosis (bone loss)
  • Osteoporotic fracturebone fracture caused by osteoporosis.
  • Projected pain from the knee joint in gonarthrosis (knee arthritis).
  • Rheumatoid arthritis – inflammatory multisystem disease, which usually manifests itself in the form of synovitis (inflammation of the synovial membrane).
  • Sacroiliitis – inflammation of the joint between the sacrum and the ilium.
  • Spinal stenosis – narrowing of the spinal canal.
  • Snapping hip syndrome (coxa saltans) – harmless, sometimes audible tendon snapping during flexion and extension of the hip joint; however, snapping hip can also contribute to bursitis of the greater trochanter (large rolling mound of the thigh bone), for example, during intense muscle training; this can lead to pain when walking

Neoplasms – tumor diseases (C00-D48).

  • Chondromatosis – occurrence of multiple benign tumors in bone.
  • Metastases (daughter tumors)
  • Tumors, unspecified

Psyche – nervous system (F00-F99; G00-G99)

  • Piriformis syndrome – compression of the sciatic nerve in the infrapiriform foramen in various local processes; severe pain in the gluteal region with radiating back pain.
  • Radicular syndromes – pain syndromes caused by the nerve roots.

Differential diagnoses for gonarthrosis (knee joint arthrosis)

Cardiovascular System (I00-I99).

  • Peripheral arterial occlusive disease (pAVD) – narrowing of peripheral arteries usually due to atherosclerosis.

Musculoskeletal system and connective tissue (M00-M99).

Neoplasms – tumor diseases (C00-D48).

  • Metastases (daughter tumors)
  • Tumors, unspecified

Psyche – nervous system (F00-F99; G00-G99)

  • Neurogenic disorders – disorders affecting the nerves.

General differential diagnoses for osteoarthritis

Blood, blood-forming organs – immune system (D50-D90).

Skin and subcutaneous (L00-L99).

  • Psoriasis (psoriasis)

Mouth, esophagus (food pipe), stomach, and intestines (K00-K67; K90-K93).

Musculoskeletal system and connective tissue (M00-M99).

  • Arthritis (inflammation of the joints)
  • Chondrocalcinosis (synonym: pseudogout); gout-like disease of the joints caused by deposition of calcium pyrophosphate in the cartilage and other tissues; leads, among other things, to joint degeneration (often of the knee joint); symptomatology resembles an acute gout attack
  • Disc hernia (herniated disc).
  • Enteropathic arthritis – occurrence of joint inflammation in the course of enterocolitis (intestinal inflammation).
  • Gout (arthritis urica/uric acid-related joint inflammation or tophic gout)/hyperuricemia (elevation of uric acid levels in the blood).
  • Behçet’s disease (synonym: Adamantiades-Behçet’s disease; Behçet’s disease; Behçet’s aphthae) – multisystem disease from the rheumatic form circle, which is associated with recurrent, chronic vasculitis (vascular inflammation) of the small and large arteries and mucosal inflammation; The triad (the occurrence of three symptoms) of aphthae (painful, erosive mucosal lesions) in the mouth and aphthous genital ulcers (ulcers in the genital region), as well as uveitis (inflammation of the middle eye skin, which consists of the choroid (choroid), the corpus ciliary (corpus ciliare) and the iris) is stated as typical for the disease; a defect in cellular immunity is suspected
  • Bekhterev’s disease (ankylosing spondylitis; Latinized Greek: spondylitis “inflammation of the vertebrae” and ankylosans “stiffening”) – chronic inflammatory rheumatic disease with pain and stiffening of joints.
  • Progressive systemic sclerosis – systemic disease with hardening of the skin and internal organs.
  • Psoriatic arthritis (arthritis due to psoriasis).
  • Reactive arthritis (synonym: post-infectious arthritis / joint inflammation) – second disease after gastrointestinal (gastrointestinal tract concerning), urogenital (urinary and genital organs concerning) or pulmonary (lungs concerning) infections; refers to an arthritis, where pathogens in the joint (usually) can not be found (sterile synovialitis).
  • Reiter’s disease (synonyms: Reiter’s syndrome; Reiter’s disease; arthritis dysenterica; polyarthritis enterica; postenteritic arthritis; posturethritic arthritis; undifferentiated oligoarthritis; urethro-oculo-synovial syndrome; Fiessinger-Leroy syndrome; English Sexually acquired reactive arthritis (SARA)) – special form of a “reactive arthritis” (see above. ); secondary disease after gastrointestinal or urogenital infections, characterized by the symptoms of Reiter’s triad; seronegative spondyloarthropathy, which is triggered especially in HLA-B27 positive persons by an intestinal or urinary tract disease with bacteria (mostly chlamydia); Can manifest as arthritis (joint inflammation), conjunctivitis (conjunctivitis), urethritis (urethritis) and partly with typical skin changes.
  • Rheumatoid arthritis – chronic inflammatory multisystem disease, which usually manifests itself in the form of synovitis – inflammation of the synovium, which produces synovial fluid. It is also called primary chronic polyarthritis (PcP).
  • Systemic lupus erythematosus (SLE) – systemic disease that affects the skin and connective tissue of the vessels, leading to vasculitides (vascular inflammation) of numerous organs such as the heart, kidneys or brain.