Overdose | Tavor® expidet®

Overdose

Taking a dose above the applied daily dose of 0.2mg – 2.5mg of the active ingredient Lorazepam may cause serious adverse side effects. The first signs of overdose are fatigue, drowsiness, and confusion. The affected patient shows a decrease in attention and responsiveness and may become increasingly drowsy.

This can lead to unconsciousness or hallucinations. A very dangerous side effect, which occurs especially in case of overdose is the decrease of muscle tension. Since the activating nerve tracts are blocked more and more, the muscles can even become slack.

This is particularly problematic with regard to the respiratory muscles. This can lead to a fatal respiratory arrest. As an antidote for poisoning with lorazepam, the active ingredient flumazenil is given.

This blocks the inhibiting neurons that have been activated too strongly and thus makes a normal stimulation of the respiratory muscles possible. Only in acute emergencies, the attending physician can administer a single dose of up to 7.5mg (with the utmost caution). This should always be done with the utmost caution and the patient should then be hospitalized for observation of possible side effects.

Is the Tavor® expidet® separable?

The Tavor® expidet® platelets are not divisible, meaning that a Tavor® 1.0 mg expidet® cannot be prescribed when the dose to be taken is actually 0.5 mg lorazepam. This is due to the fact that if one division is made, the desired dose cannot be guaranteed and there may be either more or less lorazepam in each half. However, since one wants to dose this drug precisely to achieve the desired effect, the platelet should not be divided.

Tavor® expidet® in combination with alcohol

The base price for Tavor® expidet® prescription tablets varies depending on the pack size and how many milligrams of lorazepam are in each tablet, approximately between €17 and €20 for 50 tablets. For patients with health insurance, the maximum co-payment is €5, depending on whether the patient is exempt from co-payment or not. Private patients must first pay the entire price of the medication in the pharmacy and then get the money back from the health insurance company.