Pathogenesis (disease development)
Paget’s carcinoma grows predominantly intraductally (in the glandular ducts); in approximately two-thirds of cases, there is ductal carcinoma in situ (DCIS) or deep ductal breast carcinoma.If this is not the case, it is an isolated Paget’s carcinoma.
Etiology (causes)
Disease-related causes
Neoplasms – Tumor Diseases (C00-D48).
- Breast carcinoma
If breast carcinoma (see above) is the cause of Paget’s carcinoma, then all causes listed under breast carcinoma also apply to Paget’s carcinoma (see “Causes” of breast carcinoma for details).
