The following are the most important diseases or complications that may be contributed to by Paget’s disease:
Cardiovascular system (I00-I99).
- Aortic valve stenosis – narrowing of a heart valve.
- Diffuse vascular calcifications
- Heart failure (cardiac insufficiency)
Mouth, esophagus (esophagus), stomach, and intestines (K00-K67; K90-K93).
- Tooth loss, tooth damage
Musculoskeletal system and connective tissue (M00-M99).
- Osteoarthritis
- Fractures (broken bones)
- Spinal stenosis – narrowing of the spinal canal, possibly with compression of the spinal cord.
Neoplasms – tumor diseases (C00-D48).
- Benign changes in the area of the affected bone.
- Malignant degeneration of the affected bone
- Osteosarcoma (malignant (malignant) bone tumor).
Ears – mastoid process (H60-H95)
- Hearing loss (stiffening of the ossicles, overgrowth of the cochlea/cochlea or crushing of the auditory nerve).
Psyche – nervous system (F00-F99; G00-G99).
- Neurological deficits, unspecified
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99)
- Chronic pain
- Gait disturbances, unspecified
- Headache
- Back pain
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- Airway obstructions
- Changes in the appearance of the face
