Pain during Sexual Intercourse (Dyspareunia): Test and Diagnosis

The diagnosis of dyspareunia is usually made on the basis of the medical history and physical examination.

Laboratory parameters of the 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification

  • Small blood count
  • Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate).
  • Urine status (rapid test for: nitrite, protein, hemoglobin, erythrocytes, leukocytes) incl. sediment, if necessary urine culture (pathogen detection and resistogram, that is, testing of suitable antibiotics for sensitivity / resistance).
  • Urethral swab (urethral swab) for pathogens – if urethritis (urethritis) is suspected.
    • Bacteria and fungi, possibly mycoplasma, Ureaplasma urealyticum and Chlamydia trachomatis and Neisseria gonorrhoeae; if necessary, also Chlamydia trachomatis DNA detection (Chlamydia trochmatis-PCR) or Neisseria gonorrhoeae DNA detection (Go-PCR, gonococcal PCR).
  • Pregnancy test (quantitative HCG).
  • 17-Beta estradiol (female sex hormone).
  • FSH (follicle-stimulating hormone).