Pain when urinating (Dysuria, Strangury): Test and Diagnosis

Laboratory parameters of 1st order – obligatory laboratory tests.

  • Urine status (rapid test for: pH, leukocytes, nitrite, protein, glucose, blood), sediment, if necessary urine culture (pathogen detection and resistogram, that is, testing of suitable antibiotics for sensitivity/resistance).

Laboratory parameters 2nd order – depending on the results of the history, physical examination and the obligatory laboratory parameters – for differential diagnostic clarification.

  • Small blood count
  • Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate).
  • Renal parameters – urea, creatinine.
  • Three- or four-glass sample (if prostatitis is suspected). After collecting the first and second portion of urine, the prostate is examined, massaging it a little – using a digital-rectal examination. Then the rest of the urine together with the prostate secretion is emptied into a third glass. We speak of the four-glass test if the secretion has already drained through the urethra during the prostate massage and has been collected separately. Bacterial involvement can be detected or excluded by this method. However, in clinical practice, due to time constraints, often only the two-glass sample is performed, ie collection of urine before and after prostatic massage.
  • Ejaculate analysis with determination of inflammatory mediators (a positive ejaculate culture is present at: > 103 germs/ml (relevant germ type) and leukospermia (leukocytes/white blood cells in the ejaculate), that is > 106 leukocytes/ml).